OP16.03: Sonographic characteristics of postmolar gestational trophoblastic neoplasia (GTN) at diagnosis and during follow-up
نویسندگان
چکیده
منابع مشابه
Postmolar gestational trophoblastic neoplasia: beyond the traditional risk factors.
OBJECTIVE To investigate the slope of linear regression of postevacuation serum hCG as an independent risk factor for postmolar gestational trophoblastic neoplasia (GTN). DESIGN Multicenter retrospective cohort study. SETTING Academic referral health care centers. PATIENT(S) All subjects with confirmed hydatidiform mole and at least four measurements of β-hCG titer. INTERVENTION(S) None...
متن کاملGestational trophoblastic neoplasia.
Trophoblastic neoplasms are a truly fascinating set of diseases that arise from a failed gestation. A molar pregnancy is an allograft of fetal tissue typically containing only paternal chromosomes that may invade the maternal decidua following a failed gestation that may have arisen up to decades earlier. Choriocarcinoma (CCA), the most common malignant form of trophoblastic disease, represente...
متن کاملLINE-1 Methylation Patterns as a Predictor of Postmolar Gestational Trophoblastic Neoplasia
OBJECTIVE To study the potential of long interspersed element-1 (LINE-1) methylation change in the prediction of postmolar gestational trophoblastic neoplasia (GTN). METHODS The LINE-1 methylation pattern from first trimester placenta, hydatidiform mole, and malignant trophoblast specimens were compared. Then, hydatidiform mole patients from 11999 to 2010 were classified into the following 2 ...
متن کاملDiagnosis, classification and treatment of gestational trophoblastic neoplasia.
Gestational trophoblastic neoplasia (GTN) is the term to describe a set of malignant placental diseases, including invasive mole, choriocarcinoma, placental site trophoblastic tumor and epithelioid trophoblastic tumor. Both invasive mole and choriocarcinoma respond well to chemotherapy, and cure rates are greater than 90%. Since the advent of chemotherapy, low-risk GTN has been treated with a s...
متن کاملManagement of gestational trophoblastic neoplasia
It is just 100 years since Marchand [1] identified choriocarcinoma as a tumour arising from placental villous trophoblast. Earlier description of similar tumours failed to identify their tissue of origin. Gestational Trophoblastic Disease (GTD) is the terminological umbrella now used to span the spectrum of cellular proliferations ranging from villous forms of hydatiform mole through invasive m...
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ژورنال
عنوان ژورنال: Ultrasound in Obstetrics & Gynecology
سال: 2018
ISSN: 0960-7692
DOI: 10.1002/uog.19536